ClusterMine360: A Database of Microbial PKS/NRPS Biosynthesis

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Cluster Details


Accession # AF484556.1
Cluster Bases
If cluster is a subsegment of the GenBank sequence.
Name of Compound Family Leinamycin
Synonyms
Related Compound Families
Pathway Type NRPS
Hybrid
PKS - Type I
PKS - Type I (trans-AT)
Characteristics
Producing Organism Streptomyces atroolivaceus
Phylum Actinobacteria
Organism Lineage
Actinobacteria
Actinobacteridae
Actinomycetales
Streptomycineae
Streptomycetaceae
Streptomyces
Description Streptomyces atroolivaceus leinamycin biosynthetic gene cluster, complete sequence
Sequencing References
Identification and localization of the gene cluster encoding biosynthesis of the antitumor macrolactam leinamycin in Streptomyces atroolivaceus S-140. J. Bacteriol. 2002 Dec; 184(24): 7013-24. PMID: 12446651
Type I polyketide synthase requiring a discrete acyltransferase for polyketide biosynthesis. Proc. Natl. Acad. Sci. U.S.A. 2003 Mar; 100(6): 3149-54. PMID: 12598647
Leinamycin biosynthesis revealing unprecedented architectural complexity for a hybrid polyketide synthase and nonribosomal peptide synthetase. Chem. Biol. 2004 Jan; 11(1): 33-45. PMID: 15112993
Other References
Domains Toggle View Domains
antiSMASH Status View
Status of Domain Sequence Extraction Completed
Contributor Kyle Conway
Boddy Lab

Last modified Wednesday, 07 May 2014 17:38 by System Admin